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Tmem45a gene

WebTMEM45A has 5,568 functional associations with biological entities spanning 8 categories (molecular profile, organism, chemical, functional term, phrase or reference, disease, phenotype or trait, structural feature, cell line, cell type or tissue, gene, protein or microRNA) extracted from 61 datasets. WebJul 1, 2024 · TMEM45A gene family is highly expressed in squamous epithelium, playing roles in differentiation, senescence and chemoresistance in some sort of epithelial carcinomas. The overexpression of this product may confer antiapoptotic pathways, contributing to the development of cervical squamous cell carcinoma.

Tissue expression of TMEM45A - Summary - The Human …

WebApr 1, 2014 · TMEM45A is a TMEM of 275 amino acids, predicted to have five to seven transmembrane domains and localized in the trans Golgi apparatus. Very little is known about this protein except that... WebDec 1, 2024 · Loss-of-function assays were performed using TMEM45A-targeting lentivirus to evaluate the biological role of TMEM45A in renal cancer cells. Gene set enrichment analysis (GSEA) was performed to ... kmart cosmetics thailand https://redcodeagency.com

High TMEM45A expression is correlated to epidermal …

WebTmem45a Gene Detail Summary Symbol Tmem45a Name transmembrane protein 45a Synonyms C630002M10Rik Feature Type protein coding gene IDs MGI:1913122 NCBI Gene: 56277 Alliance gene page Transcription Start Sites 16 TSS Location & Maps more Sequence Map Chr16:56625524-56706529 bp, - strand From Ensembl annotation of GRCm39 … WebDec 4, 2024 · TMEM45A is a transmembrane protein involved in tumor progression and cancer resistance to chemotherapeutic agents in hypoxic condition. It is correlated to a … WebTMEM45A. General description of the gene and the encoded protein (s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas … kmart corduroy rocking horse

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Category:TMEM45A Gene - GeneCards TM45A Protein TM45A Antibody

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Tmem45a gene

High TMEM45A expression is correlated to epidermal keratinization

WebFeb 1, 2024 · Interestingly, TMEM16A gene is amplified in different types of cancer: in 30% of esophagus cancers, in 25% of HNSCC and in 15% of breast or lung cancers. The activity of this channel modifies the MAPK pathway, which regulates cell proliferation. ... TMEM45A is a protein localized in the membrane of the Golgi apparatus which is highly expressed ... WebTMEM45A gene encodes an initially uncharacterized predicted transmembrane protein. We previously showed that this gene is highly expressed in keratinocytes where its expression correlates with ...

Tmem45a gene

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WebOct 2011 - Sep 20154 years. Namur. My research area was the dermatology. My work was dedicated to understand the function of a particular gene (TMEM45A) in keratinocyte, the main cell type of the superficial part of the skin (the epidermis), and more precisely its implication in the modification that this cell type undergoes to produce the ... WebRecombinant TMEM45A-targeting lentivirus (LV-sh-TMEM45A) or control mock lentivirus (LV-sh-NC) constructed by GenePharma (Suzhou, China) were transfected into the RCC cells. After culturing for 48–72h, puromycin was used to obtain stable clones in which the TMEM45A gene was downregulated.

WebSequence variants and/or copy number variants (deletions/duplications) within the TMEM45A gene will be detected with >99% sensitivity. Variants classified as unknown … WebCELL LINE STRUCTURE TMEM45A PATHOLOGY CANCER ANTIBODIES AND VALIDATION Dictionary Human pathology PROGNOSTIC SUMMARYi Prognostic marker in renal cancer (unfavorable) and lung cancer (unfavorable)

WebSep 6, 2012 · TMEM45A has been described to be a HIF-1 target gene in different types of cancer cells [ 34 ]. We verified that it was also the case in MDA-MB-231 cells. HIF-1α … WebShowing subcellular location of TMEM45A (DERP7, FLJ10134). We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again. TMEM45A. SECTIONS. ...

WebTruncating and splice site variants were identified in the TMEM45A gene, which fully segregate with the disorder. All affected individuals were homozygous or compound heterozygous for variants in the TMEM45A gene, while unaffected family members were heterozygous carriers. Expression analysis in healthy controls showed that TMEM45A …

WebApr 1, 2014 · In vivo, TMEM45A mRNA and protein are mostly found in the granular layer of the epidermis. TMEM45A expression is linked to keratinization, as accumulation of the … red arrows emailWebTmem45a Gene Detail Summary Symbol. Tmem45a Name. transmembrane protein 45a. Synonyms. C630002M10Rik Feature Type. protein coding gene ... Gene Model ID Feature … red arrows emojiWebJan 19, 2016 · TMEM45A gene encodes an initially uncharacterized predicted transmembrane protein. We previously showed that this gene is highly expressed in … kmart cotton ballsWebSep 8, 2024 · A study links the rare corneal disorder and variants in the TMEM45A gene. A case series found that isolated congenital keratoglobus is likely an inherited, autosomal recessive disorder. These findings were published in JAMA Ophthalmology. kmart cosco folding tableWebThe .gov means it's official. Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site. red arrows engineer deathWebShowing of 844 Results for TMEM45A Search Time: 0 ms. Export Show: Symbol Description Category UniProt ID GIFtS GC id Score; 1: TMEM45A: Transmembrane Protein 45A: Protein Coding: Q9NWC5: 37: GC03P100492: 38.78: 2: ADGRG7: Adhesion G Protein-Coupled Receptor G7 ... Gene symbols for TMEM45A. red arrows emergencyWebMar 21, 2024 · TMEM45A transmembrane protein 45A Gene ID: 55076, updated on 21-Mar-2024 Gene type: protein coding Also known as: DERP7; DNAPTP4. See all available tests … kmart cotton rugs