L'origine de réplication (aussi appelée « ori ») est une séquence unique d'ADN permettant l'initiation de la réplication. C'est à partir de cette séquence que débute une réplication unidirectionnelle ou bidirectionnelle. La structure de l'origine de réplication varie d'une espèce à l'autre ; elle est donc spécifique bien qu'elles aient toutes certaines caractéristiques. Un complexe protéique se forme au niveau de c… Origin organization, specification, and activation in eukaryotes are more complex than in bacterial or archaeal domains and significantly deviate from the paradigm established for prokaryotic replication initiation. The large genome sizes of eukaryotic cells, which range from 12 Mbp in S. … Zobacz więcej The origin of replication (also called the replication origin) is a particular sequence in a genome at which replication is initiated. Propagation of the genetic material between generations requires timely and accurate … Zobacz więcej Most bacterial chromosomes are circular and contain a single origin of chromosomal replication (oriC). Bacterial oriC regions are surprisingly diverse in size (ranging … Zobacz więcej Viruses often possess a single origin of replication. A variety of proteins have been described as being involved in viral replication. For instance, Zobacz więcej A key prerequisite for DNA replication is that it must occur with extremely high fidelity and efficiency exactly once per cell cycle to … Zobacz więcej More than five decades ago, Jacob, Brenner, and Cuzin proposed the replicon hypothesis to explain the regulation of chromosomal DNA synthesis in E. coli. The model … Zobacz więcej Archaeal replication origins share some but not all of the organizational features of bacterial oriC. Unlike bacteria, Archaea often initiate … Zobacz więcej Although DNA replication is essential for genetic inheritance, defined, site-specific replication origins are technically not a requirement for genome duplication as long as all … Zobacz więcej
Frontiers The orisome: structure and function
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Replication initiated at the origin (oriC) of the E. coli chromosome ...
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