Web** P = 0.0076 versus UBC13 pull-down of circHECW2; ## P = 0.0011 versus UBC13 pull-down of Gapdh mRNA. g Immunoprecipitation showed the binding of FTO with UBC13 in bEnd.3 cells. Data were presented by three independent experiments. * P = 0.0210 versus vector. h The bEnd.3 cells were transfected with siUBC13, the level of Ubc13 mRNA was ... WebApr 25, 2024 · Researches on methamphetamine-induced abuse have elaborated on the mechanism of miR-143 targeting PUMA and the mechanism of circHECW2 and …
Targeting circular RNAs as a therapeutic approach: …
WebThe in vivo relevance was confirmed as microinjection of circHecw2 siRNA lentivirus into the mouse hippocampus suppressed the EndoMT induced by LPS. These findings provide novel insights regarding the contribution of circHECW2 to the nonautophagic role of ATG5 in the EndoMT process in the context of drug abuse and the broad range of ... Web** P = 0.0076 versus UBC13 pull-down of circHECW2; ## P = 0.0011 versus UBC13 pull-down of Gapdh mRNA. g Immunoprecipitation showed the binding of FTO with UBC13 in bEnd.3 cells. Data were presented by three independent experiments. * P = 0.0210 versus vector. h The bEnd.3 cells were transfected with siUBC13, the level of Ubc13 mRNA was ... image to line sketch
Jie CHAO Chair Doctor of Philosophy - ResearchGate
WebTherefore, specific blockage of circHECW2 may be envisioned as a potential therapeutic target for the treatment of BBB integrity damage . In a stroke model, overexpression of … Webthat circHECW2 regulated the EndoMT by directly binding to MIR30D, a significantly downregulated miRNA from miRNA profiling, which subsequently caused an increased … WebcircHECW2 [24]. circRNA CDR1as harbors 74 seed complementary sites for miR-7, and its binding affinity for miRNAs is higher than that of any other known transcript [25]. circ3823 contributes to growth, metastasis and angiogenesis of colorectal cancer via miR-30c-5p/TCF7 axis [26]. A study by Huang et al. [27] suggested that circRNA protein image toledo