WebJul 9, 2024 · According to the 2024 ACC/AHA guideline , statins were grouped into three levels of dose intensity based on their ability to lower LDL (low-intensity, moderate-intensity and high-intensity statins). (1) low intensity statins: atorvastatin < 10 mg/day, rosuvastatin < 5 mg/day, simvastatin < 20 mg/day, and lovastatin < 40 mg/day (2) … WebCurrent guidelines recommend high-intensity or moderate-intensity statin monotherapy based on ASCVD risk, ... Lee CW, Kang SJ, Ahn JM, et al. Comparison of effects of atorvastatin (20 mg) versus rosuvastatin (10 mg) therapy on mild coronary atherosclerotic plaques (from the ARTMAP Trial). Am J Cardiol 2012;109:1700–4.
Atorvastatin (Lipitor): Basics, Side Effects & Reviews - GoodRx
WebSep 2, 2024 · Atorvastatin is highly plasma protein bound (over 98%) and has a volume of distribution of about 380 liters. Metabolism. Atorvastatin is metabolized by cytochrome … WebHigh doses — also called high-intensity statin therapy — included 40 to 80 milligrams (mg) of atorvastatin (Lipitor) or 20 to 40 mg of rosuvastatin (Crestor) daily. Examples of moderate doses include 10 to 20 mg of Lipitor and 5 to 10 mg of Crestor, the study reported. Unlike some previous studies, this study included adults over age 75. mywaseda ログイン 科目登録
Effects of High Intensity Statin Therapy on Steroid Hormones and ...
WebLimit atorvastatin dose to 20 mg/day saquinavir increases toxicity of atorvastatin by Other (see comment). Avoid or Use Alternate Drug. Comment: OATP1B1 inhibitors may increase risk of myopathy. sotorasib. sotorasib will decrease the level or effect of atorvastatin by P-glycoprotein (MDR1) efflux transporter. Avoid or Use Alternate Drug. WebAug 23, 2024 · High-intensity statin was defined as atorvastatin administered at 40–80 mg, rosuvastatin at 20–40 mg, or simvastatin at 80 mg, i.e., medication amounts higher than the standard doses described in recent guidelines [8, 9]. The inclusion criteria in the meta-analysis were: (1) RCT involving patients with a diagnosis of ACS; (2) comparison … WebDec 15, 2024 · Patients age 40-75 without diabetes or CVD, but with LDL-C 70-189 and 10-year risk >7.5%, should consider a moderate-to-high intensity statin. + Atorvastatin 40 … mywaseda ログイン